UNIVERSAL SEROLOGIC REACTION IN LEPROSY
نویسندگان
چکیده
منابع مشابه
Universal serologic reaction in leprosy.
It has long been known that the serum of certain leprosy patients gives positive reactions with tests for syphilis. These reactions have not been understood and have been interpreted as biologic ‘(false positives.” The reason for this interpretation undoubtedly lies in the widespread assumption that only in syphilis and in closely related diseases, such as yaws and bejel, are serum reactions wi...
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Kahn presents in his recent book (1) details of the latest of his contributions to serology, the concept that serological reactions with lipid antigens are phenomena common to the blood sera of all humans and animals and show distinctive patterns in health and disease. According to his method, by determining the titer of any serum with a lipid antigen in varying concentrations of saline and wit...
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BACKGROUND There is a lack of straightforward tests for field application and known biomarkers for predicting leprosy progression in infected individuals. OBJECTIVE The aim was to analyse the response to infection by Mycobacterium leprae based on the reactivity of specific antigens: natural disaccharide linked to human serum albumin via an octyl (NDOHSA), a semisynthetic phenolic glycolipid-I...
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Three patients of histopathologically confirmed borderline-tuberculoid leprosy showing no acid-fast bacilli and with lesions confined to the face, 2 on the cheek and 1 on the forehead, were given multidrug therapy as recommended by the WHO for paucibacillary cases. Within 3 months the lesions showed signs of upgrading (or reversal) reaction which was substantiated by histopathology. In 1 patien...
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Case 1: A 43 year-old, white man presented with a four month-history of six plaques well-circumscribed. Laboratory results, including several serological tests, as well as a radiological investigation, were either negative or normal. The Mitsuda reaction was positive (9 mm). He was put on prednisone therapy and multi-drug therapy (MDT) with subsequent healing of the cutaneous lesions and improv...
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ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 1951
ISSN: 0077-8923,1749-6632
DOI: 10.1111/j.1749-6632.1951.tb45830.x